HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Bromochlorobenzene → HCID 86599158, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Bromochlorobenzene | HCID 7806 | — |
| Reactant | (+/-)-(7-Amino-2,3-dihydro-1-benzofuran-2-yl)methyl 4-methylbenzenesulfonate | HCID 86599159 | — |
| Product | HCID 86599158 | HCID 86599158 | 59.7% |
Reaction Steps
Treatment of (±)-(7-amino-2,3-dihydro-1-benzofuran-2-yl)methyl 4-methylbenzenesulfonate (0.96 g, 3.0 mmol) with 1-bromo-4-chlorobenzene (0.570 g, 3.0 mmol) generally according to the procedure described for Intermediate 37 provided 0.77 g (57%) of (±)-{7-[(4-chlorophenyl)amino]-2,3-dihydro-1-benzofuran-2-yl}methyl 4-methylbenzenesulfonate as a white solid. mp 132-134° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07435837B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-8ac0d35609b14325a3e4932ba6aae272 |
| Source note | uspto-grants-2008_10 |