Dichloromethane → 5-Chloromethyl-4-(2-methoxy-ethyl)-2-(4-trifluoromethyl-phenyl)-pyrimidine
Reaction equation
[CH3:1][O:2][CH2:3][CH2:4][c:5]1[n:6][c:7](-[c:13]2[cH:14][cH:15][c:16]([C:19]([F:20])([F:21])[F:22])[cH:17][cH:18]2)[n:8][cH:9][c:10]1[CH2:11][OH:12].[Cl:27][CH2:28][Cl:29].[S:23]([Cl:24])([Cl:25])=[O:26]>>[CH3:1][O:2][CH2:3][CH2:4][c:5]1[n:6][c:7](-[c:13]2[cH:14][cH:15][c:16]([C:19]([F:20])([F:21])[F:22])[cH:17][cH:18]2)[n:8][cH:9][c:10]1[CH2:11][Cl:25]Participants
4
Sources & evidence
- ORD record
- ord-1c91587ab48349a4899c44e82073eb72
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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