Trimethylsilyl iodide → HCID 11208066, compound

Participants

Reaction Steps

The title compound was prepared (0.224 g, 74%) following the general procedure of Example 158 as a white solid, hydrochloride salt from (−)-benzyl {[7-(4-chloro-2-methylphenyl)-2,3-dihydro-1-benzofuran-2-yl]methyl}carbamate (0.40 g, 0.981 mmol) and iodotrimethylsilane (0.785 g, 3.92 mmol). [α]D25=−13.0 (c 10.0 in methanol); mp 190-191° C.

Provenance & Evidence