Methylamine → HCID 68964345, 화합물

HRID 2116363노트

반응식

CC1C=CC(S(O[CH2:12][CH:13]2[CH2:17][C:16]3[CH:18]=[C:19]([CH3:30])[CH:20]=[C:21]([C:22]4[C:27]([CH3:28])=[CH:26][CH:25]=[CH:24][C:23]=4[CH3:29])[C:15]=3[O:14]2)(=O)=O)=CC=1.[CH3:31][NH2:32]>>[CH3:29][C:23]1[CH:24]=[CH:25][CH:26]=[C:27]([CH3:28])[C:22]=1[C:21]1[C:15]2[O:14][CH:13]([CH2:12][NH:32][CH3:31])[CH2:17][C:16]=2[CH:18]=[C:19]([CH3:30])[CH:20]=1

참가 물질

반응물 2

HCID 6329Methylamine

HCID 86599328HCID 86599328, 화합물

생성물 1

HCID 68964345HCID 68964345, 화합물

실험 절차

The title compound was prepared (0.035 g, 46%) following the general procedure of Example 390 as a white solid, hydrochloride salt from (±)-[7-(2,6-dimethylphenyl) 5-methyl-2,3-dihydro-1-benzofuran-2-yl]methyl 4-methylbenzenesulfonate (0.10 g, 0.24 mmol) and methylamine (0.073 g, 2.4 mmol). mp 204-205° C.

출처 및 근거

ORD 기록: ord-474c8bc0cc204956afcb36b0614a005f
출처 데이터셋: uspto-grants-2008_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07435837B2

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