Methylamine → HCID 68962675, compound

Participants

Reaction Steps

The title compound was prepared (0.147 g, 65%) following the general procedure of Example 390 as a white solid, hydrochloride salt from (+)-[7-(2,6-dimethylphenyl)-5-fluoro-2,3-dihydro-1-benzofuran-2-yl]methyl 4-methylbenzenesulfonate (0.50 g, 1.2 mmol) and methylamine (0.372 g, 12.0 mmol). [α]D25=+1.6 (c 10.0 in methanol); mp 169-170° C.

Provenance & Evidence