Sodium Cyanide → HCID 69212273, compound

Participants

Reaction Conditions

Reaction Steps

Sodium cyanide (0.086 g) was added to a solution of the product from step (v) (0.74 g) in dimethylsulphoxide (10 ml) and heated at 60° C. for 36 h. The mixture was partitioned between ethyl acetate and brine, the organics washed with brine, dried (MgSO4) and evaporated under reduced pressure. The residue was purified by chromatography on silica eluting with 16% ethyl acetate in toluene. Yield 0.152 g

Provenance & Evidence