4-Chloroaniline → HCID 85908181, compound

Participants

Reaction Steps

A mixture of 5-allyl-2,4,6-trichloropyrimidine (7 g), 4-chloroaniline (4 g) and potassium carbonate (4.27 g) in ethanol (100 ml) was stirred at room temperature for 24 h. The mixture was partitioned between ethyl acetate and water, the organics dried (MgSO4), and evaporated under reduced pressure. The residue was purified by chromatography on silica eluting with isohexane/diethylether (2:1). Yield 5 g

Provenance & Evidence