Sodium Cyanide → HCID 9994809, compound

Participants

Reaction Conditions

Reaction Steps

Sodium cyanide (0.103 g) was added to a solution of the product from step (iii) (0.37 g) in dimethylsulphoxide (10 ml) and heated at 90° C. for 48 h. The mixture was partitioned between ethyl acetate and water, the organics dried (MgSO4) and evaporated under reduced pressure. The residue was purified by RPHPLC eluting with 29-95% acetonitrile in aqueous trifluoroacetic acid. Yield 0.14 g

Provenance & Evidence