3,4-Dimethoxybenzenesulfonyl chloride → HCID 9848527, compound

HRID 2116535Notes

Reaction equation

HRID 2116535 reaction equation
[NH2:1][C:2]1[CH:3]=[CH:4][C:5]([O:13][C:14]2[CH:15]=[C:16]([Cl:20])[CH:17]=[N:18][CH:19]=2)=[C:6]([CH:12]=1)[C:7]([O:9][CH2:10][CH3:11])=[O:8].[CH3:21][O:22][C:23]1[CH:24]=[C:25]([S:31](Cl)(=[O:33])=[O:32])[CH:26]=[CH:27][C:28]=1[O:29][CH3:30]>N1C=CC=CC=1>[CH3:21][O:22][C:23]1[CH:24]=[C:25]([S:31]([NH:1][C:2]2[CH:3]=[CH:4][C:5]([O:13][C:14]3[CH:15]=[C:16]([Cl:20])[CH:17]=[N:18][CH:19]=3)=[C:6]([CH:12]=2)[C:7]([O:9][CH2:10][CH3:11])=[O:8])(=[O:32])=[O:33])[CH:26]=[CH:27][C:28]=1[O:29][CH3:30]

Participants

4

Reactant 2

HCID 27341833,4-Dimethoxybenzenesulfonyl chlorideHCID 9948021HCID 9948021, compound

Product 1

HCID 9848527HCID 9848527, compoundYield 68%

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

The title compound was prepared in a manner similar to Example 3, beginning with 0.1 g of the aniline of Example 1 and 3,4-dimethoxybenzenesulfonyl chloride, and adding 0.2 mL of pyridine to the reaction mixture to yield 0.115 g (68%) of the title sulfonamide.

Workup

  1. customThe title compound was prepared in a manner similar to Example 3

Sources & evidence

ORD record
ord-05664cec4f1a47daa928e69467e1906d
Source dataset
uspto-grants-2008_10
Patent number
US07439242B2

Reaction notes

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