3,5-Difluorophenol → HCID 22993866, compound

HRID 2116550Notes

Reaction equation

HRID 2116550 reaction equation
Cl[C:2]1[CH:12]=[CH:11][C:10]([N+:13]([O-:15])=[O:14])=[CH:9][C:3]=1[C:4]([O:6][CH2:7][CH3:8])=[O:5].[F:16][C:17]1[CH:18]=[C:19]([OH:24])[CH:20]=[C:21]([F:23])[CH:22]=1>>[N+:13]([C:10]1[CH:11]=[CH:12][C:2]([O:24][C:19]2[CH:18]=[C:17]([F:16])[CH:22]=[C:21]([F:23])[CH:20]=2)=[C:3]([CH:9]=1)[C:4]([O:6][CH2:7][CH3:8])=[O:5])([O-:15])=[O:14]

Participants

3

Reactant 2

HCID 759283,5-DifluorophenolHCID 2774222ethyl 2-chloro-5-nitrobenzoate

Product 1

HCID 22993866HCID 22993866, compoundYield 94.7%

Procedure

Using the method described in Example 21.2, ethyl 2-chloro-5-nitrobenzoate (0.6 g) and 3,5-difluorophenol (0.34 g) were combined to provide 0.8 g of the title compound.

Sources & evidence

ORD record
ord-b628b178f25044d19667fbb8a729fc43
Source dataset
uspto-grants-2008_10
Patent number
US07439242B2

Reaction notes

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