反应详情

In a similar manner to Step 2 of Example 233, 4-(8-quinolinesulfonyloxy)-7-[1-(tert-butoxycarbonyl)-5-(piperidinomethyl)indol-2-yl]isoindolinone (0.0164 g, 0.0251 mmol) was treated with 10% hydrogen chloride-methanol solution (0.650 mL) to obtain Compound 269 (0.00555 g. yield 40%).