Trichloroacetyl chloride → 1,1-Dichlorospiro(3.3)heptan-2-one

Participants

Reaction Conditions

Reaction Steps

6.25 g of powdered zinc and then 11 ml of trichloroacetic acid chloride in solution in 170 ml of ether are added to 5 g of methylenecyclobutane in solution in ether. The solution is subjected to sonication for 3 hours while maintaining the temperature at 20° C., and then the black solution is filtered through Whatman filter. The filtrate is washed, dried, filtered and concentrated to yield the expected product in the form of a brown oil.

Provenance & Evidence