Tetrabutylammonium Fluoride → HCID 57605188, compound

Participants

Reaction Conditions

Reaction Steps

[6-(tert-Butyl-dimethyl-silanyloxy)-1H-indol-2-ylmethyl]-carbamic acid benzyl ester (0.80 g, 1.95 mmol) is dissolved in THF (2 ml). Cooled to −78° C. 1 M TBAF solution in THF (3.90 ml) is added. The reaction mixture is concentrated and the residue is purified by column chromatography (30% ethyl acetate in hexanes) to obtain (6-Hydroxy-1H-indol-2-ylmethyl)-carbamic acid benzyl ester.

Provenance & Evidence