Mycophenolic Acid → MYCOPHENOLATE SODIUM

Participants

Reaction Steps

Mycophenolic acid (3.20 g, 10 mmol) was dissolved in 1,4-dioxane (64 ml). To this solution sodium methoxide (9 mmol, 1.67 ml of its 30% methanolic solution) was added under stirring. After 1 hour stirring at room temperature the solid was filtered off. The polymorphism was determined by X-ray diffraction from this wet sample. The obtained material was form M26.

Provenance & Evidence