反应详情

1.33 g (11.34 mmol) of N,N-diethyltrimethylsilylamine are added over the course of 5 minutes at room temperature and with vigorous stirring to 2.50 g (10.22 mmol) of 1,3-dimethyl-2-chloroimidazolidinium methylsulfate in 10 ml of dry chloroform. The solvent is distilled off, and the residue is washed three times with 5 ml of diethyl ether and subsequently dried under a reduced pressure of 7.0 Pa and at 50° C. for 1 hour. The product is crystallised from a mixture of tetrahydrofuran:diethyl ether (1:1), giving 2.22 g of 1,3-dimethyl-2-dimethylaminoimidazolidinium methylsulfate, corresponding to a yield of 85.7%.

1. distillationThe solvent is distilled off
2. washthe residue is washed three times with 5 ml of diethyl ether
3. customsubsequently dried under a reduced pressure of 7.0 Pa and at 50° C. for 1 hour
4. customThe product is crystallised from a mixture of tetrahydrofuran:diethyl ether (1:1)