Acetonitrile → 1,3-Dimethyl-2-chloroimidazolidinium dimethylphosphate

HRID 2116869Notes

Reaction equation

HRID 2116869 reaction equation
[CH3:1][N:2]1[CH2:6][CH2:5][N:4]([CH3:7])[C:3]1(Cl)[Cl:8].[CH3:10][O:11][P:12]([O-:16])([O:14][CH3:15])=[O:13].[Na+].C(#N)C>O>[CH3:10][O:11][P:12]([O-:16])([O:14][CH3:15])=[O:13].[CH3:1][NH+:2]1[CH2:6][CH2:5][N:4]([CH3:7])[CH:3]1[Cl:8]

Participants

5

Reactant 3

HCID 6342AcetonitrileHCID 127556762,2-Dichloro-1,3-dimethylimidazolidineHCID 23663684Sodium dimethyl phosphate

Product 1

HCID 693109381,3-Dimethyl-2-chloroimidazolidinium dimethylphosphateYield 95.6%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

3.00 g (17.75 mmol) of 1,3-dimethyl-2,2-dichloroimidazolidine and 2.63 g (17.77 mmol) of sodium dimethylphosphate are mixed with 20 ml of acetonitrile and 2 ml of water. The reaction mixture is stirred for 12 hours at room temperature, and the precipitate NaCl is subsequently filtered off. The solvent is distilled off, and the residue is dried for 6 hours under a reduced pressure of 7 Pa and at an oil-bath temperature of 70-80° C., giving 4.39 g of 1,3-dimethyl-2-chloroimidazolidinium dimethylphosphate, corresponding to a yield of 95.6%.

Workup

  1. filtrationthe precipitate NaCl is subsequently filtered off
  2. distillationThe solvent is distilled off
  3. customthe residue is dried for 6 hours under a reduced pressure of 7 Pa and at an oil-bath temperature of 70-80° C.

Sources & evidence

ORD record
ord-28be6be4c7904f76a7187b0e0a542c19
Source dataset
uspto-grants-2008_10
Patent number
US07439395B2

Reaction notes

Loading…