1-Cyclopropyl-3-(2-fluoro-4-iodo-phenylamino)-1H-pyrrolo[3,2-c]pyridine-2-carboxylic acid (2-hydroxy-ethoxy)-amide → 1-Cyclopropyl-3-(2-fluoro-4-methylsulfanyl-phenylamino)-1H-pyrrolo[3,2-c]pyridine-2-carboxylic acid (2-hydroxy-ethoxy)-amide
Reaction equation
[CH:29](=[CH2:30])[O:31][CH2:32][CH2:33][O:34][NH:35][C:36](=[O:37])[c:38]1[c:39]([NH:50][c:51]2[c:52]([F:59])[cH:53][c:54]([S:57][CH3:58])[cH:55][cH:56]2)[c:40]2[cH:41][n:42][cH:43][cH:44][c:45]2[n:46]1[CH:47]1[CH2:48][CH2:49]1.[OH:1][CH2:2][CH2:3][O:4][NH:5][C:6]([c:7]1[n:8]([CH:9]2[CH2:10][CH2:11]2)[c:12]2[cH:13][cH:14][n:15][cH:16][c:17]2[c:18]1[NH:19][c:20]1[cH:21][cH:22][c:23]([I:24])[cH:25][c:26]1[F:27])=[O:28]>>[OH:31][CH2:32][CH2:33][O:34][NH:35][C:36](=[O:37])[c:38]1[c:39]([NH:50][c:51]2[c:52]([F:59])[cH:53][c:54]([S:57][CH3:58])[cH:55][cH:56]2)[c:40]2[cH:41][n:42][cH:43][cH:44][c:45]2[n:46]1[CH:47]1[CH2:48][CH2:49]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-2b2a673d11a142648eefb1577b3a2336
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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