HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → (+/-)-5-chloro-4-ethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | 1-(2-Amino-6-chlorophenyl)propan-1-ol | HCID 69318120 | — |
| Product | (+/-)-5-chloro-4-ethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one | HCID 69318495 | 73% |
Reaction Steps
This compound was prepared using General Method 2 (EXAMPLE 1) from (±)-1-(2-amino-6-chlorophenyl)propan-1-ol (0.18 g, 0.94 mmol) to afford 0.14 g (73%) of (±)-5-chloro-4-ethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one after flash chromatography (4:1 hexanes:ethyl acetate).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07442696B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-f2dd17fd376043c5a533b12aa0f265fd |
| Source note | uspto-grants-2008_10 |