HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-6-chlorobenzaldehyde → (+/-)-(2-Amino-6-chlorophenyl)-cyclopentyl-methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-6-chlorobenzaldehyde | HCID 22399512 | — |
| Reactant | HCID 178419650 | HCID 178419650 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | (+/-)-(2-Amino-6-chlorophenyl)-cyclopentyl-methanol | HCID 69315836 | 36% |
Reaction Steps
This compound was prepared using General Method 1 (EXAMPLE 1) from 2-amino-6-chlorobenzaldehyde (0.30 g, 1.9 mmol) and cyclopentylmagnesium bromide (2 M in ether, 1.9 mL)) to afford 0.16 g (36%) of (±)-(2-amino-6-chlorophenyl)-cyclopentyl-methanol after flash chromatography (4:1 hexanes:ethyl acetate).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07442696B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-ada438d7963c4adbb6c39fe67aac7a39 |
| Source note | uspto-grants-2008_10 |