Diethyl Ether → HCID 69315370, compound

HRID 2117282Notes

Reaction equation

HRID 2117282 reaction equation
[NH2:1][C:2]1[CH:11]=[C:10]([Cl:12])[CH:9]=[CH:8][C:3]=1C(OC)=O.[CH3:13][Mg]Br.CC[O:18][CH2:19][CH3:20]>>[NH2:1][C:2]1[CH:11]=[C:10]([Cl:12])[CH:9]=[CH:8][C:3]=1[C:19]([OH:18])([CH3:20])[CH3:13]

Participants

4

Reactant 3

HCID 3283Diethyl EtherHCID 80001Methyl 4-chloroanthranilateHCID 178418573HCID 178418573, compound

Product 1

HCID 69315370HCID 69315370, compound

Procedure

This compound was prepared using General Method 1 (EXAMPLE 1) from methyl 2-amino-4-chlorobenzoate (2.8 g) and methyl magnesium bromide (3 M in diethyl ether, 20 mL) in 75 mL ether to afford 2-(2-amino-4-chlorophenyl)propan-2-ol.

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-9025c4020f06468b807f329b0adcf0e2
Source dataset
uspto-grants-2008_10
Patent number
US07442696B2

Reaction notes

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