Diethyl Ether → 2-(2-Amino-3-methylphenyl)propan-2-ol

HRID 2117283Notes

Reaction equation

HRID 2117283 reaction equation
[NH2:1][C:2]1[C:11](C)=[CH:10][CH:9]=[CH:8][C:3]=1[C:4](OC)=O.[CH3:13][Mg]Br.CC[O:18][CH2:19][CH3:20]>>[NH2:1][C:2]1[C:3]([CH3:4])=[CH:8][CH:9]=[CH:10][C:11]=1[C:19]([OH:18])([CH3:20])[CH3:13]

Participants

4

Reactant 3

HCID 3283Diethyl EtherHCID 2763406Methyl 3-methylanthranilateHCID 178418573HCID 178418573, compound

Product 1

HCID 139590002-(2-Amino-3-methylphenyl)propan-2-ol

Procedure

This compound was prepared using General Method 1 (EXAMPLE 1) from methyl 2-amino-3-methylbenzoate and methyl magnesium bromide (3 M in diethyl ether) in ether to afford 2-(2-amino-3-methylphenyl)propan-2-ol.

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-d57b19b38cae4c1b9d1545c9ec5d6ba6
Source dataset
uspto-grants-2008_10
Patent number
US07442696B2

Reaction notes

Loading…