HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexene → Methyl 4-[(1-hydroxy-2-methylindolizin-3-yl)carbonyl]benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexene | HCID 8079 | — |
| Reactant | Methyl 4-[(1-(benzyloxy)-2-methylindolizin-3-yl)carbonyl]benzoate | HCID 12069558 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Methyl 4-[(1-hydroxy-2-methylindolizin-3-yl)carbonyl]benzoate | HCID 12069595 | — |
Reaction Steps
8.75 ml (86.37 mmol) of cyclohexene are added to 3.45 g (8.64 mmol) of methyl 4-[(1-(benzyloxy)-2-methylindolizin-3-yl)carbonyl]benzoate in 40 ml of ethanol, in the presence of 690 mg of 10% Pd/C, and the medium is heated under reflux for one hour.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07442708B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-3b72034fc4cd4f8f980689cea2c1a895 |
| Source note | uspto-grants-2008_10 |