3-Methoxybenzyl bromide → HCID 12069597, compound

HRID 2117375Notes

Reaction equation

HRID 2117375 reaction equation
[OH:1][C:2]1[C:3]([CH3:23])=[C:4]([C:11]([C:13]2[CH:22]=[CH:21][C:16]([C:17]([O:19][CH3:20])=[O:18])=[CH:15][CH:14]=2)=[O:12])[N:5]2[C:10]=1[CH:9]=[CH:8][CH:7]=[CH:6]2.[CH3:24][O:25][C:26]1[CH:27]=[C:28]([CH:31]=[CH:32][CH:33]=1)[CH2:29]Br>>[CH3:24][O:25][C:26]1[CH:27]=[C:28]([CH:31]=[CH:32][CH:33]=1)[CH2:29][O:1][C:2]1[C:3]([CH3:23])=[C:4]([C:11]([C:13]2[CH:22]=[CH:21][C:16]([C:17]([O:19][CH3:20])=[O:18])=[CH:15][CH:14]=2)=[O:12])[N:5]2[C:10]=1[CH:9]=[CH:8][CH:7]=[CH:6]2

Participants

3

Reactant 2

HCID 40672073-Methoxybenzyl bromideHCID 12069595Methyl 4-[(1-hydroxy-2-methylindolizin-3-yl)carbonyl]benzoate

Product 1

HCID 12069597HCID 12069597, compound

Procedure

This compound is obtained according to the same procedure as that of Example 86, by O-alkylation of methyl 4-[(1-hydroxy-2-methylindolizin-3-yl)carbonyl]benzoate with 3-methoxybenzyl bromide. A yellow powder is obtained which melts at 106° C.

Workup

  1. customThis compound is obtained
  2. customA yellow powder is obtained which melts at 106° C.

Sources & evidence

ORD record
ord-d514478714874a6988253b3dd1eb3dd1
Source dataset
uspto-grants-2008_10
Patent number
US07442708B2

Reaction notes

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