Ethyl bromoacetate → HCID 68707120, compound

HRID 2117382Notes

Reaction equation

HRID 2117382 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([C:10]2[N:18]3[C:13]([CH:14]=[CH:15][CH:16]=[CH:17]3)=[C:12]([O:19][CH3:20])[C:11]=2[CH3:21])=[O:9])=[CH:4][C:3]=1[O:22][CH3:23].Br[CH2:25][C:26]([O:28][CH2:29][CH3:30])=[O:27]>>[CH3:23][O:22][C:3]1[CH:4]=[C:5]([C:8]([C:10]2[N:18]3[C:13]([CH:14]=[CH:15][CH:16]=[CH:17]3)=[C:12]([O:19][CH3:20])[C:11]=2[CH3:21])=[O:9])[CH:6]=[CH:7][C:2]=1[NH:1][CH2:25][C:26]([O:28][CH2:29][CH3:30])=[O:27]

Participants

3

Procedure

This compound was obtained according to the same procedure as that described in Example 192, by alkylating (4-amino-3-methoxyphenyl)(1-methoxy-2-methylindolizin-3-yl)methanone, a compound of Example 94, with ethyl bromoacetate. A yellow powder is obtained.

Workup

  1. customThis compound was obtained
  2. customA yellow powder is obtained

Sources & evidence

ORD record
ord-aaea769510864bddbad24d2b6f0f355b
Source dataset
uspto-grants-2008_10
Patent number
US07442708B2

Reaction notes

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