Ethyl bromoacetate → HCID 68706037, compound

HRID 2117384Notes

Reaction equation

HRID 2117384 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([C:10]2[N:18]3[C:13]([CH:14]=[CH:15][CH:16]=[CH:17]3)=[C:12]([O:19][CH3:20])[C:11]=2[C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)=[O:9])=[CH:4][C:3]=1[O:27][CH3:28].Br[CH2:30][C:31]([O:33][CH2:34][CH3:35])=[O:32]>>[CH3:28][O:27][C:3]1[CH:4]=[C:5]([C:8]([C:10]2[N:18]3[C:13]([CH:14]=[CH:15][CH:16]=[CH:17]3)=[C:12]([O:19][CH3:20])[C:11]=2[C:21]2[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=2)=[O:9])[CH:6]=[CH:7][C:2]=1[NH:1][CH2:30][C:31]([O:33][CH2:34][CH3:35])=[O:32]

Participants

3

Reactant 2

HCID 7748Ethyl bromoacetateHCID 12069603HCID 12069603, compound

Product 1

HCID 68706037HCID 68706037, compound

Procedure

This compound was obtained according to the method described in Example 192, by alkylating (4-amino-3-methoxyphenyl)(1-methoxy-2-phenylindolizin-3-yl)methanone, a compound of Example 95, with ethyl bromoacetate. A yellow powder is obtained.

Workup

  1. customThis compound was obtained
  2. customA yellow powder is obtained

Sources & evidence

ORD record
ord-61fb4edd69cc4ccc919262a5bcd5de23
Source dataset
uspto-grants-2008_10
Patent number
US07442708B2

Reaction notes

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