Sodium Hydroxide → HCID 68709416, compound

HRID 2117385Notes

Reaction equation

HRID 2117385 reaction equation
COC1C=C(C(C2N3C(C=CC=C3)=C(OC)C=2C)=O)C=CC=1NCC(O)=O.[CH3:28][O:29][C:30]1[CH:42]=[C:41]([C:43]([C:45]2[N:53]3[C:48]([CH:49]=[CH:50][CH:51]=[CH:52]3)=[C:47]([O:54][CH3:55])[C:46]=2[C:56]2[CH:61]=[CH:60][CH:59]=[CH:58][CH:57]=2)=[O:44])[CH:40]=[CH:39][C:31]=1[NH:32][CH2:33][C:34]([O:36]CC)=[O:35].[OH-].[Na+]>>[CH3:28][O:29][C:30]1[CH:42]=[C:41]([C:43]([C:45]2[N:53]3[C:48]([CH:49]=[CH:50][CH:51]=[CH:52]3)=[C:47]([O:54][CH3:55])[C:46]=2[C:56]2[CH:61]=[CH:60][CH:59]=[CH:58][CH:57]=2)=[O:44])[CH:40]=[CH:39][C:31]=1[NH:32][CH2:33][C:34]([OH:36])=[O:35]

Participants

4

Reactant 3

HCID 14798Sodium HydroxideHCID 68706037HCID 68706037, compound2×HCID 68706657HCID 68706657, compound

Product 1

HCID 68709416HCID 68709416, compound

Procedure

Obtained according to the same procedure as the compound of Example 196, by saponification of ethyl 2-{2-methoxy-4-[(1-methoxy-2-phenylindolizin-3-yl)carbonyl]anilino}acetate, a compound of Example 197, with 1 N sodium hydroxide. A yellow powder is obtained.

Workup

  1. customObtained
  2. customA yellow powder is obtained

Sources & evidence

ORD record
ord-5bad3bdfa94a446a8b06abdc952265e1
Source dataset
uspto-grants-2008_10
Patent number
US07442708B2

Reaction notes

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