HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(trifluoromethyl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidine → (4-Methanesulfonyl-biphenyl-2-yl)-(2-trifluoromethyl-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(trifluoromethyl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidine | HCID 53471483 | — |
| Reactant | 4-(methylsulfonyl)-Biphenyl-2-carboxylic acid | HCID 57445254 | — |
| Product | (4-Methanesulfonyl-biphenyl-2-yl)-(2-trifluoromethyl-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl)-methanone | HCID 58677901 | — |
Reaction Steps
Prepared in analogy to example 1.1 from 2-trifluoromethyl-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidine (CA [74737-17-7]; WO2004069162) and 4-methanesulfonyl-biphenyl-2-carboxylic acid (example 2.5). MS (m/e): 462.0 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07442710B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-3cf16ca591434722b002ececcf43d90d |
| Source note | uspto-grants-2008_10 |