HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2,3,4-Tetrahydroisoquinoline-6-carbonitrile → 2-(2-Isopropoxy-5-methanesulfonyl-benzoyl)-1,2,3,4-tetrahydro-isoquinoline-6-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2,3,4-Tetrahydroisoquinoline-6-carbonitrile | HCID 10241065 | — |
| Reactant | 2-Isopropoxy-5-methylsulfonylbenzoic acid | HCID 21100237 | — |
| Product | 2-(2-Isopropoxy-5-methanesulfonyl-benzoyl)-1,2,3,4-tetrahydro-isoquinoline-6-carbonitrile | HCID 11531400 | — |
Reaction Steps
Prepared in analogy to example 1.1 from 6-cyano-1,2,3,4-tetrahydro-isoquinoline (CA [166398-34-1]) and 2-isopropoxy-5-methanesulfonyl-benzoic acid (Example 2.1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07442710B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-0a819b0767f748f8939487a4a312bbbc |
| Source note | uspto-grants-2008_10 |