2-Isopropoxy-5-methylsulfonylbenzoic acid → HCID 57445258, compound

HRID 2117414Notes

Reaction equation

HRID 2117414 reaction equation
[CH3:1][N:2]([CH3:13])[C:3]1[CH:12]=[C:11]2[C:6]([CH2:7][CH2:8][NH:9][CH2:10]2)=[CH:5][CH:4]=1.[CH:14]([O:17][C:18]1[CH:26]=[CH:25][C:24]([S:27]([CH3:30])(=[O:29])=[O:28])=[CH:23][C:19]=1[C:20](O)=[O:21])([CH3:16])[CH3:15]>>[CH3:1][N:2]([CH3:13])[C:3]1[CH:12]=[C:11]2[C:6]([CH2:7][CH2:8][N:9]([C:20]([C:19]3[CH:23]=[C:24]([S:27]([CH3:30])(=[O:29])=[O:28])[CH:25]=[CH:26][C:18]=3[O:17][CH:14]([CH3:16])[CH3:15])=[O:21])[CH2:10]2)=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 211002372-Isopropoxy-5-methylsulfonylbenzoic acidHCID 24257340N,N-Dimethyl-1,2,3,4-tetrahydroisoquinolin-7-amine

Product 1

HCID 57445258HCID 57445258, compound

Procedure

Prepared in analogy to example 1.1 from dimethyl-(1,2,3,4-tetrahydro-isoquinolin-7-yl)-amine (CA [138276-84-3]) and 2-isopropoxy-5-methanesulfonyl-benzoic acid (Example 2.1).

Sources & evidence

ORD record
ord-a363f9bd2398437b8e2254d2382089ba
Source dataset
uspto-grants-2008_10
Patent number
US07442710B2

Reaction notes

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