6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline → HCID 58677886, compound

HRID 2117416Notes

Reaction equation

HRID 2117416 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][C:12]=1[O:13][CH3:14])[CH2:9][NH:8][CH2:7][CH2:6]2.[CH:15]([O:18][C:19]1[CH:27]=[CH:26][C:25]([S:28]([CH3:31])(=[O:30])=[O:29])=[CH:24][C:20]=1[C:21](O)=[O:22])([CH3:17])[CH3:16]>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][C:12]=1[O:13][CH3:14])[CH2:9][N:8]([C:21]([C:20]1[CH:24]=[C:25]([S:28]([CH3:31])(=[O:30])=[O:29])[CH:26]=[CH:27][C:19]=1[O:18][CH:15]([CH3:17])[CH3:16])=[O:22])[CH2:7][CH2:6]2

Participants

3

Reactant 2

HCID 156236,7-Dimethoxy-1,2,3,4-TetrahydroisoquinolineHCID 211002372-Isopropoxy-5-methylsulfonylbenzoic acid

Product 1

HCID 58677886HCID 58677886, compound

Procedure

Prepared in analogy to example 1.1 from 6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline (CA [1745-07-9]) and 2-isopropoxy-5-methanesulfonyl-benzoic acid (Example 2.1).

Sources & evidence

ORD record
ord-f88531ddf267417ea0ea8574904e092e
Source dataset
uspto-grants-2008_10
Patent number
US07442710B2

Reaction notes

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