Isoquinoline, 7,8-dichloro-1,2,3,4-tetrahydro- → HCID 11662202, compound

HRID 2117418Notes

Reaction equation

HRID 2117418 reaction equation
[Cl:1][C:2]1[C:11]([Cl:12])=[C:10]2[C:5]([CH2:6][CH2:7][NH:8][CH2:9]2)=[CH:4][CH:3]=1.[CH:13]([O:16][C:17]1[CH:25]=[CH:24][C:23]([S:26]([CH3:29])(=[O:28])=[O:27])=[CH:22][C:18]=1[C:19](O)=[O:20])([CH3:15])[CH3:14]>>[Cl:1][C:2]1[C:11]([Cl:12])=[C:10]2[C:5]([CH2:6][CH2:7][N:8]([C:19]([C:18]3[CH:22]=[C:23]([S:26]([CH3:29])(=[O:28])=[O:27])[CH:24]=[CH:25][C:17]=3[O:16][CH:13]([CH3:15])[CH3:14])=[O:20])[CH2:9]2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 123920Isoquinoline, 7,8-dichloro-1,2,3,4-tetrahydro-HCID 211002372-Isopropoxy-5-methylsulfonylbenzoic acid

Product 1

HCID 11662202HCID 11662202, compound

Procedure

Prepared in analogy to example 1.1 from 7,8-dichloro-1,2,3,4-tetrahydro-isoquinoline (CA [61563-24-4]) and 2-isopropoxy-5-methanesulfonyl-benzoic acid (Example 2.1).

Sources & evidence

ORD record
ord-c5af794a800a4eb68db6a3b746b06ee9
Source dataset
uspto-grants-2008_10
Patent number
US07442710B2

Reaction notes

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