6-Methoxy-1,2,3,4-tetrahydroisoquinoline → HCID 11509625, compound

HRID 2117432Notes

Reaction equation

HRID 2117432 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[CH2:9][NH:8][CH2:7][CH2:6]2.[CH:13]([O:16][C:17]1[CH:25]=[CH:24][C:23]([S:26]([CH3:29])(=[O:28])=[O:27])=[CH:22][C:18]=1[C:19](O)=[O:20])([CH3:15])[CH3:14]>>[CH:13]([O:16][C:17]1[CH:25]=[CH:24][C:23]([S:26]([CH3:29])(=[O:28])=[O:27])=[CH:22][C:18]=1[C:19]([N:8]1[CH2:7][CH2:6][C:5]2[C:10](=[CH:11][CH:12]=[C:3]([O:2][CH3:1])[CH:4]=2)[CH2:9]1)=[O:20])([CH3:15])[CH3:14]

Participants

3

Reactant 2

HCID 393566-Methoxy-1,2,3,4-tetrahydroisoquinolineHCID 211002372-Isopropoxy-5-methylsulfonylbenzoic acid

Product 1

HCID 11509625HCID 11509625, compound

Procedure

Prepared in analogy to example 1.1 from 6-methoxy-1,2,3,4-tetrahydro-isoquinoline (CA [42923-77-3]) and 2-isopropoxy-5-methanesulfonyl-benzoic acid (Example 2.1).

Sources & evidence

ORD record
ord-57fb5afce4764c1a98ae69770d3521af
Source dataset
uspto-grants-2008_10
Patent number
US07442710B2

Reaction notes

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