7-Cyano-1,2,3,4-tetrahydroisoquinoline → HCID 58677876, compound

HRID 2117440Notes

Reaction equation

HRID 2117440 reaction equation
[C:1]([C:3]1[CH:12]=[C:11]2[C:6]([CH2:7][CH2:8][NH:9][CH2:10]2)=[CH:5][CH:4]=1)#[N:2].[CH:13]([O:16][C:17]1[CH:25]=[CH:24][C:23]([S:26]([CH3:29])(=[O:28])=[O:27])=[CH:22][C:18]=1[C:19](O)=[O:20])([CH3:15])[CH3:14]>>[CH:13]([O:16][C:17]1[CH:25]=[CH:24][C:23]([S:26]([CH3:29])(=[O:28])=[O:27])=[CH:22][C:18]=1[C:19]([N:9]1[CH2:8][CH2:7][C:6]2[C:11](=[CH:12][C:3]([C:1]#[N:2])=[CH:4][CH:5]=2)[CH2:10]1)=[O:20])([CH3:15])[CH3:14]

Participants

3

Reactant 2

HCID 101762437-Cyano-1,2,3,4-tetrahydroisoquinolineHCID 211002372-Isopropoxy-5-methylsulfonylbenzoic acid

Product 1

HCID 58677876HCID 58677876, compound

Procedure

Prepared in analogy to example 1.1 from 7-cyano-1,2,3,4-tetrahydro-isoquinoline (CA [149355-52-2]) and 2-isopropoxy-5-methanesulfonyl-benzoic acid (Example 2.1).

Sources & evidence

ORD record
ord-7b4ee503567342ad913a649a05f8250c
Source dataset
uspto-grants-2008_10
Patent number
US07442710B2

Reaction notes

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