Methanol → 4-(2,2-Difluorovinyl)-1-{[6-methoxy-2-(trifluoromethyl)imidazo[1,2-b]pyridazin-3-yl]methyl}pyrrolidin-2-one
Reaction equation
[CH3:26][O-:27].[CH3:30][OH:31].[Cl:1][c:2]1[cH:3][cH:4][c:5]2[n:6]([n:7]1)[c:8]([CH2:15][N:16]1[C:17](=[O:25])[CH2:18][CH:19]([CH:21]=[C:22]([F:23])[F:24])[CH2:20]1)[c:9]([C:11]([F:12])([F:13])[F:14])[n:10]2.[Na+:28].[OH2:29]>>[c:2]1([O:27][CH3:26])[cH:3][cH:4][c:5]2[n:6]([n:7]1)[c:8]([CH2:15][N:16]1[C:17](=[O:25])[CH2:18][CH:19]([CH:21]=[C:22]([F:23])[F:24])[CH2:20]1)[c:9]([C:11]([F:12])([F:13])[F:14])[n:10]2Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-f82298c4934b43b88f4f8e76c4226363
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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