2-(Dimethylamino)ethanol → HCID 178506692, compound

Participants

Reaction Conditions

Reaction Steps

A hexane (150 ml) solution of N,N-dimethylaminoethanol (21.0 ml, 210.0 mmol) was dropwise added to a hexane solution of n-butyllithium (266 ml, 1.58 M, 420.0 mmol) at 5° C. while 1 hour. Next, a hexane (15 ml) solution of 2-phenylpyridine (15.0 ml, 105.0 mmol) was dropwise added to the mixture at 5° C. while 20 minutes. A hexane solution of 2-lithio-6-phenylpyridine was prepared by the mixture stirred at 5° C. for 1 hour additionally.

Provenance & Evidence