Dimethylformamide → HCID 12192482, compound

Participants

Reaction Steps

A mixture of furopyrrole 12 (0.9 g, 2.7 mmol), methyl tosylate (750 mg, 4.04 mmol), potassium carbonate (1 g, 7.2 mmol) and dimethyl formamide was stirred at room temperature overnight. Water was then added, and the organic component extracted with DCM. The solvent was removed, and washing with water then methanol gave the methylated compound 13 as a red solid (0.652 g, 70%), m.p. 253-255° C. δH (CDCl3) 8.55 and 8.38 (4H, AA′BB′, Ar), 7.88-7.84 (2H, m, o-Ph), 7.65-7.60 (3H, m, m/p-Ph) and 3.49 (3H, s, NCH3). λmax (abs) (DCM)/nm 482 ( 17,462)

Provenance & Evidence