N-Methyl-2-(2-nitrophenyl)ethan-1-amine → 2-[2-(Methylamino)ethyl]aniline

Participants

Reaction Steps

A mixture of N-methyl-N-(2-(2-nitrophenyl)ethyl)amine (WO 9803473, pg 100) (3 g, 16.65 mmol) and Raney® nickel (500 mg) in ethanol (50 ml) was hydrogenated at 60 psi and room temperature for 2 hours. The mixture was filtered through Celite® and the filtrate evaporated under reduced pressure to give the title compound as an oil.

Provenance & Evidence