Pivaloyl chloride → HCID 21925604, compound

HRID 2118032Notes

Reaction equation

HRID 2118032 reaction equation
[CH3:1][C:2]([CH3:7])([CH3:6])[C:3]([Cl:5])=[O:4].[Cl:8][C:9]1[CH:34]=[CH:33][C:12]2[N:13]3[C:17]([CH2:18][NH:19][CH2:20][C:11]=2[CH:10]=1)=[N:16][N:15]=[C:14]3[CH:21]1[CH2:26][CH2:25][N:24]([C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][N:28]=2)[CH2:23][CH2:22]1>>[ClH:5].[ClH:8].[Cl:8][C:9]1[CH:34]=[CH:33][C:12]2[N:13]3[C:17]([CH2:18][N:19]([C:3](=[O:4])[C:2]([CH3:7])([CH3:6])[CH3:1])[CH2:20][C:11]=2[CH:10]=1)=[N:16][N:15]=[C:14]3[CH:21]1[CH2:22][CH2:23][N:24]([C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][N:28]=2)[CH2:25][CH2:26]1

Participants

3

Reactant 2

HCID 62493Pivaloyl chlorideHCID 113264888-Chloro-1-(3,4,5,6-tetrahydro-2h-[1,2']bipyridinyl-4-yl)-5,6-dihydro4h-2,3,5,10b-tetraaza-benzo[e]azulene

Product 1

HCID 21925604HCID 21925604, compoundYield 54%

Procedure

The title compound was prepared from 2,2-Dimethyl-propionyl chloride and the amine of example 4, in 54% yield, using the procedure described in example 8.

Sources & evidence

ORD record
ord-6075918e14ff4197ab42090b5b14c616
Source dataset
uspto-grants-2008_10
Patent number
US07442795B2

Reaction notes

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