Acetone → HCID 21925564, compound

HRID 2118035Notes

Reaction equation

HRID 2118035 reaction equation
[Cl:1][C:2]1[CH:27]=[CH:26][C:5]2[N:6]3[C:10]([CH2:11][NH:12][CH2:13][C:4]=2[CH:3]=1)=[N:9][N:8]=[C:7]3[CH:14]1[CH2:19][CH2:18][N:17]([C:20]2[N:25]=[CH:24][CH:23]=[CH:22][N:21]=2)[CH2:16][CH2:15]1.[CH3:28][C:29]([CH3:31])=O>>[Cl:1][C:2]1[CH:27]=[CH:26][C:5]2[N:6]3[C:10]([CH2:11][N:12]([CH:29]([CH3:31])[CH3:28])[CH2:13][C:4]=2[CH:3]=1)=[N:9][N:8]=[C:7]3[CH:14]1[CH2:19][CH2:18][N:17]([C:20]2[N:21]=[CH:22][CH:23]=[CH:24][N:25]=2)[CH2:16][CH2:15]1

Participants

3

Reactant 2

HCID 180AcetoneHCID 21925629HCID 21925629, compound

Product 1

HCID 21925564HCID 21925564, compoundYield 65%

Procedure

The title compound was prepared from acetone and the amine of example 12, in 65% yield, using the procedure described in example 13.

Sources & evidence

ORD record
ord-61bd978332494f34beca3a89f609a9ab
Source dataset
uspto-grants-2008_10
Patent number
US07442795B2

Reaction notes

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