Acetyl chloride → HCID 21925605, compound

HRID 2118038Notes

Reaction equation

HRID 2118038 reaction equation
[C:1](Cl)(=[O:3])[CH3:2].[Cl:5][C:6]1[CH:31]=[CH:30][C:9]2[N:10]3[C:14]([CH2:15][NH:16][CH2:17][C:8]=2[CH:7]=1)=[N:13][N:12]=[C:11]3[CH:18]1[CH2:23][CH2:22][N:21]([C:24]2[N:29]=[CH:28][CH:27]=[CH:26][N:25]=2)[CH2:20][CH2:19]1>>[Cl:5][C:6]1[CH:31]=[CH:30][C:9]2[N:10]3[C:14]([CH2:15][N:16]([C:1](=[O:3])[CH3:2])[CH2:17][C:8]=2[CH:7]=1)=[N:13][N:12]=[C:11]3[CH:18]1[CH2:23][CH2:22][N:21]([C:24]2[N:25]=[CH:26][CH:27]=[CH:28][N:29]=2)[CH2:20][CH2:19]1

Participants

3

Reactant 2

HCID 6367Acetyl chlorideHCID 21925629HCID 21925629, compound

Product 1

HCID 21925605HCID 21925605, compoundYield 37%

Procedure

The title compound was prepared from acetyl chloride and the amine of example 12, in 37% yield, using the procedure described in example 3.

Sources & evidence

ORD record
ord-1c35b3254e7345d69eda655cf92b2140
Source dataset
uspto-grants-2008_10
Patent number
US07442795B2

Reaction notes

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