4-t-Butylbenzenesulfonyl chloride → HCID 11259430, compound

Participants

Reaction Steps

The title compound was prepared from ethyl 5-nitro-3-phenyl-1H-indole-2-carboxylate and 4-tert-butylbenzene sulfonyl chloride followed the procedures of Example 1 Step 2 & Step 3 as a gray solid: 1H NMR (DMSO-d6) δ 1.25 (s, 9H, 7.05 (d, J=1.8 Hz, 1H, 7.10 (dd, J=8.9, 2.0 Hz, 1H, 7.26-7.45 (m, 6H, 7.54 (d, J=8.9 Hz, 2H, 7.57 (d, J=8.8 Hz, 2H, 9.81 (s, 1H, 11.79 (s, 1H, 12.42 (br s, 1H; MS (ESI) m/z 447 [M-H]−; HRMS calcd for C25H25N2O4S: 449.1533; found (ESI+): 449.1524; Anal. calcd for C25H24N2O4S.0.25H2O: C, 66.27; H, 5.45; N, 6.18. Found: C, 65.98; H, 5.34; N, 6.14.

Provenance & Evidence