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HRID2118164

反应详情

EQUATION

反应方程式

HRID 2118164 的结构方程式

REACTANTS

反应物

2
结构：CC(=O)O
HCID176

Acetic Acid

C2H4O2

结构：CC(=O)O.CC1(C)OCc2cc([C@@H](O)CNCCCCCCOCCCCc3cccc(S(N)(=O)=O)c3)ccc2O1.NS(=O)(=O)c1cccc(CCCCOCCCCCCNC[C@H](O)c2ccc(O)c(CO)c2)c1
HCID86609662

未命名化合物

PRODUCTS

生成物

1
结构：CC(=O)O.NS(=O)(=O)c1cccc(CCCCOCCCCCCNC[C@H](O)c2ccc(O)c(CO)c2)c1
HCID42625819

未命名化合物

收率 220.7%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：O
溶剂HCID962

Water

H2O

PROCEDURE

实验过程

3-(4-{[6-({(2R)-2-Hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl}amino)hexyl]oxy}butyl)benzenesulfonamide acetate 3-{4-[(6-{[(2R)-2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-hydroxyethyl]amino}hexyl)oxy]butyl}benzenesulfonamide (0.283 g) was stirred with acetic acid (8 ml) and water (4 ml) at 70° for 35 min before evaporating to dryness. The residue was re-evaporated twice with toluene to give the title compound (0.318 g) LCMS RT=2.34 min ES+ve 495 (MH)+.

WORKUP

后处理

  1. custombefore evaporating to dryness
  2. customThe residue was re-evaporated twice with toluene