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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2118171Generated: November 1, 2026

3-{4-[(6-{[2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-hydroxyethyl]amino}hexyl)oxy]butyl}benzenesulfonamide → 3-{4-[(6-{[(2S)-2-(2,2-Dimethyl-4H-1,3-benzodioxin-6-yl)-2-hydroxyethyl]amino}hexyl)oxy]butyl}benzenesulfonamide

https://huagongshe.com/reaction/2118171

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-{4-[(6-{[2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-hydroxyethyl]amino}hexyl)oxy]butyl}benzenesulfonamideHCID 21895473—
SolventEthanol heptaneHCID 22502148—
Product3-{4-[(6-{[(2S)-2-(2,2-Dimethyl-4H-1,3-benzodioxin-6-yl)-2-hydroxyethyl]amino}hexyl)oxy]butyl}benzenesulfonamideHCID 4262559023.8%

Reaction Steps

Resolution of 3-{4-[(6-{[2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-hydroxyethyl]amino}hexyl)oxy]butyl}benzenesulfonamide (0.403 g) on an HPLC Chiralcel OJ column using 40% ethanol/heptane afforded the title compound (0.096 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07442836B2
Source datasetuspto-grants-2008_10
ORD IDord-64dbc66640534c38a7894271b030d4fc
Source noteuspto-grants-2008_10