1-Methylpiperazine → HCID 11283637, compound

Participants

Reaction Steps

Treatment of compound 32 with N-methylpiperazine as described in Example 19 (Step 2) afforded the title compound, 34, as an off-white solid. 1HNMR (400 MHz, DMSO-d6): δ 0.85 (t, 3H), 2.11 (s, 3H), 2.27 (br, 4H), 2.39 (q, 2H), 2.50 (br, 4H), 3.38 (s, 2H), 6.49 (d, J=16 Hz, 1H), 6.79 (d, J=8.6 Hz, 2H), 6.85 (d, J=8.6 Hz, 2H), 7.09-7.19 (m, 5H), 7.23 (d, J=8.1 Hz, 2H), 7.49 (d, J=16 Hz, 1H), 7.65 (d, J=8 Hz, 2H), 12.36 (br, 1H); MS m/z 511 (M+H)+.

Provenance & Evidence