HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-{4-[(6-Bromohexyl)oxy]-1-butyn-1-yl}-3-(cyclopentylsulfonyl)benzene → 1-{4-[(6-Bromohexyl)oxy]butyl}-3-(cyclopentylsulfonyl)benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-{4-[(6-Bromohexyl)oxy]-1-butyn-1-yl}-3-(cyclopentylsulfonyl)benzene | HCID 69119823 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 1-{4-[(6-Bromohexyl)oxy]butyl}-3-(cyclopentylsulfonyl)benzene | HCID 69119827 | — |
Reaction Steps
To an evacuated flask, containing palladium on carbon [50% water by weight] (43 mg) was added a solution of 1{4-[(6-bromohexyl)oxy]-1-butyn-1-yl}-3-(cyclopentylsulfonyl) benzene (304 mg) in EtOAc (10 ml). The mixture was hydrogenated for 19 h. The catalyst was filtered off and the filtrate was concentrated in vacuo to afford title compound. LCMS RT=3.92 min
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07442839B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-79ec8e1c85984fe5a2e3834e64d3a175 |
| Source note | uspto-grants-2008_10 |