HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 69119808, compound → HCID 10098658, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 69119808 | HCID 69119808 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 10098658 | HCID 10098658 | — |
Reaction Steps
To an evacuated flask containing palladium on carbon [50% water by weight] was added a solution of (1R)-2-{[6-({4-[3-(cyclopentylsulfonyl)phenyl]butyl}oxy)hexyl]amino)-1-{3-fluoro-4-[(phenylmethyl)oxy]phenyl}ethanol (37 mg) in EtOAc (8 ml) and AcOH (2 ml). The reaction mixture was hydrogenated for 4 h. The catalyst was filtered off and the filtrate concentrated in vacuo to give the title compound. LCMS RT=2.60 min 535(M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07442839B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-03fe939cfadd4b37aa03408d4491543e |
| Source note | uspto-grants-2008_10 |