Sodium ethoxide → HCID 20193699, compound

Participants

Reaction Steps

The title compound was prepared from ethyl 6-(4-methoxy-2-pyridinyl)-3-(1-methylethyl)-5-oxohexanoate and ethanolic sodium ethoxide, refluxing for 2 hours according to the procedure of Example 2. The product separated from the aqueous phase as a yellow solid upon adjusting the pH to about 6 and was recovered by extraction with dichloromethane. Evaporation of the dried extract and recrystallization from acetonitrile gave the product as a white solid, mp 152°-154.5° C. The confirmatory elemental analysis is shown in Table II.

Provenance & Evidence