Citric Acid → Calcium Carbonate

HRID 2118458Notes

Reaction equation

HRID 2118458 reaction equation
[C:1]([OH:13])(=[O:12])[CH2:2][C:3]([CH2:8][C:9]([OH:11])=[O:10])([C:5]([OH:7])=[O:6])[OH:4].[C:14](=[O:17])([O-:16])[O-:15].[Ca+2:18]>C(O)C>[C:14](=[O:15])([O-:17])[O-:16].[Ca+2:18].[C:1]([O-:13])(=[O:12])[CH2:2][C:3]([CH2:8][C:9]([O-:11])=[O:10])([C:5]([OH:7])=[O:6])[OH:4].[Ca+2:18]

Participants

5

Reactant 2

HCID 311Citric Acid2×HCID 10112Calcium Carbonate

Product 2

HCID 10112Calcium CarbonateHCID 243631185-56-4

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
40 °C

Procedure

A mixture of 22 parts citric acid having a grain size between 0.4 and 0.6 mm and 43 parts citric acid of a grain size of about 0.1 mm were mixed, heated to 40° C., and mixed with 10 parts of a 50% ethanol solution. After five minutes of oscillating mixture, evacuation to 500 mbar was carried out and 20 parts of micronized calcium carbonate were introduced. Without agitation, evacuation was carried out again and when the pressure reached 500 mbar, mixing was carried out in an oscillating fashion and the valve to the vacuum pump was turned off. The resulting reaction permitted the pressure to rise slowly, and upon attaining a vacuum of 200 mbar pressure, full vacuum was applied. The difference in the overlying space pursuant to calculation of the pressure difference yields a conversion of approximately 4% of the quantity of calcium carbonate to monocalcium citrate.

Workup

  1. additionwere mixed
  2. additionmixing
  3. customThe resulting reaction

Sources & evidence

ORD record
ord-0bbbd6c51d23488db06fd21da92a7d08
Source dataset
uspto-grants-1987_07
Patent number
US04678661

Reaction notes

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