Acetic Anhydride → HCID 20193946, compound

HRID 2118493Notes

Reaction equation

HRID 2118493 reaction equation
[NH2:1][C:2]1[S:3][C:4]([S:7][CH2:8][C:9]([C:17]2[CH:22]=[CH:21][C:20]([Cl:23])=[CH:19][C:18]=2[Cl:24])([OH:16])[CH2:10][N:11]2[CH:15]=[N:14][CH:13]=[N:12]2)=[N:5][N:6]=1.[C:25](OC(=O)C)(=[O:27])[CH3:26]>N1C=CC=CC=1>[C:25]([NH:1][C:2]1[S:3][C:4]([S:7][CH2:8][C:9]([C:17]2[CH:22]=[CH:21][C:20]([Cl:23])=[CH:19][C:18]=2[Cl:24])([OH:16])[CH2:10][N:11]2[CH:15]=[N:14][CH:13]=[N:12]2)=[N:5][N:6]=1)(=[O:27])[CH3:26]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 20193940HCID 20193940, compound

Product 1

HCID 20193946HCID 20193946, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

1-[3-(2-Amino-1,3,4-thiadiazol-5-ylthio)-2-(2,4-dichlorophenyl)-2-hydroxy-propyl]-1,2,4-triazole (0.5 g, 0.00124 m) was stirred at room temperature with a mixture of acetic anhydride (0.5 ml) and pyridine (5 ml) for one hour. The resulting solid was collected by filtration, washed with water and dried to give the title compound, 0.44 g (80%); m.p. 132° C.

Workup

  1. filtrationThe resulting solid was collected by filtration
  2. washwashed with water
  3. customdried

Sources & evidence

ORD record
ord-07bf2b12d1924b7c9c0277239b04771c
Source dataset
uspto-grants-1987_07
Patent number
US04678789

Reaction notes

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