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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2118510Generated: October 31, 2026

Benzene, 1-(chloromethyl)-2-fluoro- → 2-(2-Fluorobenzyl)-6,7-dimethoxy-3,4-dihydroisoquinolinium chloride

https://huagongshe.com/reaction/2118510

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzene, 1-(chloromethyl)-2-fluoro-HCID 9580—
Reactant3,4-Dihydro-6,7-dimethoxyisoquinolineHCID 30058—
Solvent1,2-DichloroethaneHCID 11—
Product2-(2-Fluorobenzyl)-6,7-dimethoxy-3,4-dihydroisoquinolinium chlorideHCID 12000792—

Reaction Steps

The title compound is prepared analogously to Example A from 6,7-dimethoxy-3,4-dihydroisoquinoline and 2-fluorobenzyl chloride in ethylene chloride. Melting point: 196°-198° C. (Decomp.)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04678792
Source datasetuspto-grants-1987_07
ORD IDord-bad56d8baeea49e2b1c16761ec36dc38
Source noteuspto-grants-1987_07